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MBC 201 CBT PRACTICE TEST

Phil

February 9, 2024

Take your time to read instructions before taking this test.

There are 40 questions which you are to answer in 15 minutes that gives you roughly 30 seconds per question.

If you can get at least 60%, you can be rest assured that you’ll ace MBC 201 exam

In a normal exam you will be asked between 40 – 60 questions but I only arranged 40 questions

Note

Do not be in a hurry to answer the questions

Do not waste time on a question you don’t know

Move as fast as possible and starting with questions that don’t have calculation first to save time

Always crosscheck

Don’t be in a hurry to submit, you are not in a competition

Don’t be scared. Getting an A is easy

Don’t be over confident, you can end up a D, E or F. Calm your blood, no be only you sabi book

Please do well to use our comment box incase there’s a message you want to pass to us

70 – 100 A

60 – 69 B

50 – 59 C

45 – 49 D

40 – 44 E

0 – 39 F

I wish you success

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MBC 201

1 / 40

1. Which of the following temperature best suits the growth and multiplication of transformed cells?

A. 26°C

B. 30°C

C. 25°C

D. 37°C

2 / 40

2. Which of the following enzyme is used in PCR?

A. EcoRI

B. Taq DNA polymerase

C. HRP

D. EcoRII

3 / 40

3. During prolonged fasting, the body source its major metabolic fuel through which of the following metabolic events;

A. Hepatic gluconeogenesis

B. Hepatic and skeletal muscle glycogenesis

C. Amino acid breakdown to ketone bodies

D. Hepatic conversion of acetyl coA from FA oxidation

4 / 40

4. Which is an aldose sugar?

A. Glyceraldehydes 3-phosphate

B. Fructose 1,6-biphosphate

C. All the options

D. Dihydroxyacetone phosphate

5 / 40

5. The relationship between oxygen concentration and the fraction of binding sites occupied in myoglobin can best be described as ________

A. Linear with a positive slope

B. Linear with a negative slope

C. Hyperbolic

D. Parabolic

6 / 40

6. Which of the following hormone is responsible for the activation of phospholipase C?

A. Vasopressin

B. Adrenaline

C. Cortisol

D. Serotonin

7 / 40

7. Splitting of 1,3 Diphosphoglycerate is catalyzed by;

A. Aldolase

B. Phosphoglycerate kinase

C. None of the options

D. Triose phosphate isomerise

8 / 40

8. Which of the following catalyzes the reversible degradation of 2-phosphoglycerate to phosphoenolpyruvate?

A. Enolase

B. Trypsin

C. Chymotrypsin

D. Hexokinase

9 / 40

9. Disorders of fatty acid oxidation include;

A. Carnitine deficiency

B. Ketoacidosis

C. All the options

D. Carnitine deficiency

10 / 40

10. The stability of an α-helix is not affected by which of the following?

A. Electrostatic repulsion

B. I nteraction between R groups spaced three residues apart

C. Bulkiness

D. Occurrence of alanine and glycine residues

11 / 40

11. Which of the following statements is correct about column chromatography?

A. Mobile phase is a porous solid material kept in the column with appropriate chemical characteristics

B. Mobile phase is a porous solid material kept in the column with appropriate chemical characteristics

C. Resolution improves as column length increases

D. Large proteins exit the column faster than tiny proteins

12 / 40

12. Who deduced the double-helical structure of DNA?

A. Anton van Leeuwenhoek

B. Frederick Sanger

C. Mendel

D. Watson and Francis Crick

13 / 40

13. Splitting of Fructose 1, 6 biphosphate is catalyzed by;

A. Triose phosphate isomerise

B. Hexokinase

C. Phosphofructokinase

D. Aldolase

14 / 40

14. Non pathologic forms of ketosis are due to;

A. Refsum's disease

B. The post absorptive phase of severe exercise

C. Jamaican Vomiting sickness

D. Diabetic ketoacidosis

15 / 40

15. The number of milligrams of KOH required to neutralize the free and combined fatty acid in one gram of a given fat is called __________

A. Acid number

B. Polenske number

C. Iodine number

D. Saponification number

16 / 40

16. When compared to the first immune response to the same antigen, which of the following is not a hallmark of the secondary immune response?

A. Antibody produced has a greater affinity for the antigen

B. Antibody is generated fast

C. Many antibodies are produced

D. Antibody is generated without T-cell help

17 / 40

17. The process of β-oxidation of fatty acids includes all but one of the process

A. Hydration of the unsaturated fatty acyl CoA

B. Oxidation of fatty acyl CoA

C. Oxidation of the β-hydroxy derivative

D. None of the options

18 / 40

18. How many types of signal transducers are there?

A. 7

B. 4

C. 8

D. 6

19 / 40

19. Which is not true about carnitine deficiency?

A. It is not treatable

B. It occurs particularly in the preterm infants

C. It is due to inadequate biosynthesis

D. Symptoms include hypoglycemia, lipid accumulation and muscular weakness

20 / 40

20. The first stage of the glycolytic pathway has______ chemical reaction steps

A. 10

B. 3

C. 4

D. 7

21 / 40

21. The heat of vaporization of water is ________

A. 1260 kJ/g

B. 2260 J/g

C. 2060 kJ/g

D. 1060 J/g

22 / 40

22. The breakdown of one molecule of Glucose will yield ------ molecules of pyruvate

A. Three

B. Four

C. Five

D. Two

23 / 40

23. Which of the following is a intracellular second messengers?

A. Glycine

B. Acetylcholine

C. Glutamate

D. IP3

24 / 40

24. The digestive enzyme that completes digestion of small peptides within the intestinal mucosal cells is ______,

A. Arginine

B. Enteropeptidase

C. Aminopeptidase

D. Oligopeptides

25 / 40

25. The enzymes involved in ketogenesis are

A. All the options

B. HMGcoA lyase

C. β-ketothiolase

D. HMG-coA synthase

26 / 40

26. Splitting of Fructose 1, 6 biphosphate yields ----- molecules of glyceraldehyde 3- phosphate

A. 2

B. 3

C. 4

D. 5

27 / 40

27. Which of the following proteins does not function in cell-cell interaction?

A. Cytochrome c

B. Cadherin

C. Integrin

D. N-CAM

28 / 40

28. Which of the following are important for white blood cell recognition?

A. Proteoglycans

B. Glycolipids

C. Glycoproteins

D. Glycosaminoglycans

29 / 40

29. Which is not true about cellular fatty acid metabolism?

A. None of the options

B. Fatty acid activation occurs in the cytosol as fatty acyl CoAs

C. Fatty acid oxidation occurs in the mitochondrial matrix

D. Free fatty acids travels through the blood stream bound to serum albumin

30 / 40

30. Which of the following is a 39-residue hormone of the anterior pituitary gland?

A. Bradykinin

B. Glucagon

C. Insulin

D. Corticotropin

31 / 40

31. Which of the following is true about phosphodiester linkage?

A. 5’-phosphate group of one nucleotide unit is joined to the 5’-hydroxyl group of the next nucleotide

B. 3’-phosphate group of one nucleotide unit is joined to the 5’-hydroxyl group of the next nucleotide

C. 3’-phosphate group of one nucleotide unit is joined to the 3’-hydroxyl group of the next nucleotide

D. 5’-phosphate group of one nucleotide unit is joined to the 3’-hydroxyl group of the next nucleotide

32 / 40

32. Which of the following is not correct about phosphorylation by IRS on serine residue?

A. It increases insulin levels

B. It is molecular mechanism for insulin resistance

C. It is an inhibitory phosphorylation

D. Target tissues fail to respond to circulating insulin

33 / 40

33. Arrangement of nucleotides in DNA can be seen using which of the following instruments?

A. Ultracentrifuge

B. Light microscope

C. X-Ray crystallography

D. Electron microscope

34 / 40

34. Which of the following is true about the Z-DNA helix?

A. It has alternating GC sequences

B. It has fewer base pairs per turn than B-DNA

C. It tends to be found at the 3’ end of the genes

D. It is a permanent conformation of DNA

35 / 40

35. Which of the following is abundantly found in collagen?

A. Alanine

B. Tryptophan

C. Glycine

D. Serine

36 / 40

36. All but one is true about the carnitine fatty acyl carrier system

A. Mitochondrial Carnitine acyl transferase II re-synthesizes fatty acyl CoA

B. Carnitine acyl transferase 1 facilitates synthesis of Acyl carnitine

C. Free carnitine remains in the mitochondrial matrix

D. Carninitine acyl translocase transports acyl carnitine across the inner mitochondrial membrane into the matrix

37 / 40

37. Utilization of fatty acids for energy production is absent in which of these tissues

A. Skeletal muscle

B. Brain

C. Red blood cells

D. Cardiac muscle

38 / 40

38. Which of the following enzyme catalyzes a reaction that introduces reduced nitrogen ito cellular metabolism?

A. Bacterial glutamine synthase

B. Bacterial denitrogenate reductase

C. Phosphatase

D. Bacterial denitrogenate oxidase

39 / 40

39. Cellular energy currency is in form of;

A. All the options

B. ATP

C. ADP

D. Phosphates

40 / 40

40. Which of the following is termed as conserved gene order?

A. Ortholog

B. Microarray

C. Paralog

D. Synteny

Your score is

The average score is 27%

MBC 201 CBT PRACTICE TEST

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